Halmekyto, M.: search on Z-Library

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1

Transgenic Animals as Bioproducers of Therapeutic Proteins

Jänne, Juhani, Hyttinen, Juha-Matti, Peura, Teija, Tolvanen, Minna, Alhonen, Leena, Halmekytö, Maria

Journal:

Annals of Medicine

Year:

1992

Language:

english

File:

PDF, 1.39 MB

english, 1992

2

Effects of Serum-Free In Vitro Maturation of Bovine Oocytes on Subsequent Embryo Development and Cell Allocation in Two Developmental Stages of Day 7 Blastocysts

K Korhonen, K Kananen, E Ketoja, J Matomäki, M Halmekytö, J Peippo

Journal:

Reproduction in Domestic Animals

Year:

2010

Language:

english

File:

PDF, 121 KB

english, 2010

3

Hexokinase II-deficient Mice: PRENATAL DEATH OF HOMOZYGOTES WITHOUT DISTURBANCES IN GLUCOSE TOLERANCE IN HETEROZYGOTES

Heikkinen, S., Pietila, M., Halmekyto, M., Suppola, S., Pirinen, E., Deeb, S. S., Janne, J., Laakso, M.

Journal:

Journal of Biological Chemistry

Year:

1999

Language:

english

File:

PDF, 231 KB

english, 1999

4

Transgenic mice over-expressing the human spermidine synthase gene

Kauppinen, L, Myöhänen, S, Halmekytö, M, Alhonen, L, Jänne, J

Journal:

Biochemical Journal

Year:

1993

Language:

english

File:

PDF, 708 KB

english, 1993

5

Use of transgenic animals as models for studying the neurobiological role of ornithine decarboxylase expression

Kauppinen, R.A., Halmekytö, M., Lukkarinen, J., Gröhn, O.J.M., Sinervirta, R., Alhonen, L., Jänne, J.

Journal:

Biological Psychiatry

Year:

1997

Language:

english

File:

PDF, 250 KB

english, 1997

6

Correlation of Polyamine and Growth Responses to N 1,N 11-Diethylnorspermine in Primary Fetal Fibroblasts Derived from Transgenic Mice Overexpressing Spermidine/SpermineN 1-Acetyltransferase

Alhonen, L., Karppinen, A., Uusi-Oukari, M., Vujcic, S., Korhonen, V.-P., Halmekyto, M., Kramer, D. L., Hines, R., Janne, J., Porter, C. W.

Journal:

Journal of Biological Chemistry

Year:

1998

Language:

english

File:

PDF, 610 KB

english, 1998

7

Altered Levels of Growth-related and Novel Gene Transcripts in Reproductive and Other Tissues of Female Mice Overexpressing Spermidine/Spermine N 1-Acetyltransferase (SSAT)

Min, S. H., Simmen, R. C. M., Alhonen, L., Halmekyto, M., Porter, C. W., Janne, J., Simmen, F. A.

Journal:

Journal of Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 1000 KB

english, 2002

8

Methylation of human ornithine decarboxylase gene before transfection abolishes its transient expression in Chinese hamster ovary cells

Maria Halmekytö, Ari Hirvonen, Jarmo Wahlfors, Leena Alhonen, Juhani Jänne

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 932 KB

english, 1989

9

Preserved induction of long-term potentiation in the stratum radiatum in CA1 field of hippocampal slices from transgenic mice overexpressing ornithine decarboxylase and overproducing putrescine

R. Pussinen, J. Sirviö, L. Alhonen, J. Larson, M. Halmekytö, E. Koivisto, J. Jänne

Journal:

Pathophysiology

Year:

1998

Language:

english

File:

PDF, 147 KB

english, 1998

10

Tissue-specific expression of the prostatic acid phosphatase promoter constructs

Jingdong Shan, Katja Porvari, Anne Kivinen, Lila Patrikainen, Maria Halmekytö, Juhani Jänne, Pirkko Vihko

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 215 KB

english, 2003

11

Position-independent, aberrant expression of the human ornithine decarboxylase gene in transgenic mice

Maria Halmekytö, Leena Alhonen, Jarmo Wahlfors, Riitta Sinervirta, Olli A. Janne, Juhani Jänne

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 425 KB

english, 1991

12

Regulation of the expression of human ornithine decarboxylase gene and ornithine decarboxylase promoter-driven reporter gene in transgenic mice

Halmekytö, M, Hyttinen, J M, Sinervirta, R, Leppänen, P, Jänne, J, Alhonen, L

Journal:

Biochemical Journal

Year:

1993

Language:

english

File:

PDF, 1.44 MB

english, 1993

13

Transgenic mice overexpressing ornithine and S -adenosylmethionine decarboxylases maintain a physiological polyamine homoeostasis in their tissues

HELJASVAARA, Ritva, VERESS, Ildiko, HALMEKYTÖ, Maria, ALHONEN, Leena, JÄNNE, Juhani, LAAJALA, Pasi, PAJUNEN, Antti

Journal:

Biochemical Journal

Year:

1997

Language:

english

File:

PDF, 254 KB

english, 1997

14

The effect of ascorbic acid during biopsy and cryopreservation on viability of bovine embryos produced in vivo

K. Korhonen, H. Julkunen, K. Kananen, P. Bredbacka, T. Tiirikka, M. Räty, K. Vartia, I. Kaimio, A. Kontinen, M. Halmekytö, J. Vilkki, J. Peippo, H. Lindeberg

Journal:

Year:

2012

Language:

english

File:

PDF, 386 KB

english, 2012

15

Generation of Transgenic Dairy Cattle from Transgene-Analyzed and Sexed Embryos Produced In Vitro

Hyttinen, Juha-Matti, Peura, Teija, Tolvanen, Minna, Aalto, Jussi, Alhonen, Leena, Sinervirta, Riitta, Halmekytö, Maria, Myöhänen, Sanna, Jänne, Juhani

Journal:

Year:

1994

File:

PDF, 427 KB

1994

16

Preserved induction of long-term potentiation in the stratum radiatum in the CA1 field of hippocampal slices from transgenic mice overexpressing ornithine decarboxylase and overproducing putrescine

R. Pussinen, J. Sirviö, L. Alhonen, J. Larson, M. Halmekytö, E. Koivisto, J. Jänne

Journal:

Year:

1998

Language:

english

File:

PDF, 55 KB

english, 1998

17

Levels of ornithine decarboxylase genomic sequences, heterogeneous nuclear RNA and mRNA in human myeloma cells resistant to α -difluoromethylornithine

Hyttinen, J M, Halmekytö, M, Alhonen, L, Jänne, J

Journal:

Biochemical Journal

Year:

1991

Language:

english

File:

PDF, 845 KB

english, 1991

18

Nuclear Magnetic Resonance Spectroscopy Study on Energy Metabolism, Intracellular pH, and Free Mg2+ Concentration in the Brain of Transgenic Mice Overexpressing Human Ornithine Decarboxylase Gene

Risto A. Kauppinen, Maria Halmekyto, Leena Alhonen, Juhani Jaime

Journal:

Journal of Neurochemistry

Year:

1992

Language:

english

File:

PDF, 632 KB

english, 1992

19

Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue

SUPPOLA, Suvikki, PIETILÄ, Marko, PARKKINEN, Jyrki J., KORHONEN, Veli-Pekka, ALHONEN, Leena, HALMEKYTÖ, Maria, PORTER, Carl W., JÄNNE, Juhani

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 216 KB

english, 1999

20

Polyamines and regulation of spermatogenesis: selective stimulation of late spermatogonia in transgenic mice overexpressing the human ornithine decarboxylase gene.

Hakovirta, H, Keiski, A, Toppari, J, Halmekytö, M, Alhonen, L, Jänne, J, Parvinen, M

Journal:

Molecular Endocrinology

Year:

1993

Language:

english

File:

PDF, 875 KB

english, 1993

21

Induced expression of neurotrophins in transgenic mice overexpressing ornithine decarboxylase and overproducing putrescine

M. Reeben, J. Arbatova, J. Palgi, R. Miettinen, M. Halmekytö, L. Alhonen, J. Jänne, P. Riekkinen Sr., M. Saarma

Journal:

Journal of Neuroscience Research

Year:

1996

Language:

english

File:

PDF, 749 KB

english, 1996

22

Enhanced papilloma formation in response to skin tumor promotion in transgenic mice overexpressing the human ornithine decarboxylase gene

Maria Halmekytö, Karl Syrjänen, Juhani Jänne, Leena Alhonen

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 301 KB

english, 1992

23

Molecular Cloning of a cDNA Encoding Human Spermine Synthase

KORHONEN, VELI-PEKKA, HALMEKYTÖ, MARIA, KAUPPINEN, LEILA, MYÖHÄNEN,, SANNA, WAHLFORS, JARMO, KEINÄNEN, TUOMO, HYVÖNEN, TAPANI, ALHONEN, LEENA, ELORANTA, TERHO, JÄNNE, JUHANI

Journal:

DNA and Cell Biology

Year:

1995

Language:

english

File:

PDF, 2.75 MB

english, 1995

24

Impact of in vitro fertilization of bovine oocytes with sex-sorted frozen–thawed spermatozoa on developmental kinetics, quality and sex ratio of developing embryos

Peippo, J., Räty, M., Korhonen, K., Eronen, M., Kananen, K., Hurme, T., Halmekytö, M., Mäki-Tanila, A.

Journal:

Year:

2010

Language:

english

File:

PDF, 106 KB

english, 2010

25

Elevated Seizure Threshold and Impaired Spatial Learning in Transgenic Mice with Putrescine Overproduction in the Brain

T. Halonen, J. Sivenius, R. Miettinen, M. Halmekytö, R. Kauppinen, R. Sinervirta, L. Alakuijala, L. Alhonen, E. MacDonald, J. Jänne, P. J. Riekkinen Sr

Journal:

European Journal of Neuroscience

Year:

1993

Language:

english

File:

PDF, 1.41 MB

english, 1993

26

Life-long over-expression of ornithine decarboxylase (ODC) gene in transgenic mice does not lead to generally enhanced tumorigenesis or neuronal degeneration

Leena Alhonen, Maria Halmekytö, Veli-Matti Kosma, Jarmo Wahlfors, Risto Kauppinen, Juhani Jänne

Journal:

International Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 374 KB

english, 1995

27

Transgenic bioreactors

Juhani Jänne, Juha-Matti Hyttinen, Teija Peura, Minna Tolvanen, Leena Alhonen, Rlitta Sinervirta, Maria Halmekytö

Journal:

International Journal of Biochemistry

Year:

1994

Language:

english

File:

PDF, 1.21 MB

english, 1994

28

Transgenic mice expressing the human ornithine decarboxylase gene under the control of mouse metallothionein I promoter

ALHONEN, Leena, HEIKKINEN, Sami, SINERVIRTA, Riitta, HALMEKYTÖ, Maria, ALAKUIJALA, Pekka, JÄNNE, Juhani

Journal:

Biochemical Journal

Year:

1996

Language:

english

File:

PDF, 267 KB

english, 1996

29

Endothelial-specific gene expression directed by the tie gene promoter in vivo

Korhonen, J, Lahtinen, I, Halmekyto, M, Alhonen, L, Janne, J, Dumont, D, Alitalo, K

Journal:

Year:

1995

File:

PDF, 3.09 MB

1995

30

Cerebral Energy Metabolism and Immediate Early Gene Induction Following Severe Incomplete Ischaemia in Transgenic Mice Overexpressing the Human Ornithine Decarboxylase Gene: Evidence that Putrescine is not Neurotoxic In Vivo

Jouko Lukkarainen, Risto A. Kauppinen, Jari Koistinaho, Maria Halmekytö, Leena Alhonen, Juhani Jänne

Journal:

European Journal of Neuroscience

Year:

1995

Language:

english

File:

PDF, 1.64 MB

english, 1995

31

Activation of Polyamine Catabolism Profoundly Alters Tissue Polyamine Pools and Affects Hair Growth and Female Fertility in Transgenic Mice Overexpressing Spermidine/SpermineN 1-Acetyltransferase

Pietila, M., Alhonen, L., Halmekyto, M., Kanter, P., Janne, J., Porter, C. W.

Journal:

Journal of Biological Chemistry

Year:

1997

Language:

english

File:

PDF, 499 KB

english, 1997

32

Human ornithine decarboxylase-encoding loci: nucleotide sequence of the expressed gene and characterization of a pseudogene

Jänne, Juhani, Jänne, Olli A., Hickok, Noreen J., Wahlfors, Jarmo, Crozat, Anne, Halmekytö, Maria, Albonen, Leena

Journal:

Year:

1990

Language:

english

File:

PDF, 1.58 MB

english, 1990

33

Tissue-Specific Expression of Rat Light Neurofilament Promoter-Driven Reporter Gene in Transgenic Mice

M. Reeben, M. Halmekyto, L. Alhonen, R. Sinervirta, M. Saarma, J. Janne

Journal:

Biochemical and Biophysical Research Communications

Year:

1993

File:

PDF, 435 KB

1993

34

Characterization of a transgenic mouse line over-expressing the human ornithine decarboxylase gene

Halmekytö, M, Alhonen, L, Wahlfors, J, Sinervirta, R, Eloranta, T, Jänne, J

Journal:

Biochemical Journal

Year:

1991

Language:

english

File:

PDF, 781 KB

english, 1991

35

Transgenic mice over-producing putrescine in their tissues do not convert the diamine into higher polyamines

Halmekytö, M, Alhonen, L, Alakuijala, L, Jänne, J

Journal:

Biochemical Journal

Year:

1993

Language:

english

File:

PDF, 638 KB

english, 1993

36

Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue

SUPPOLA, Suvikki, PIETILÄ, Marko, PARKKINEN, Jyrki J., KORHONEN, Veli-Pekka, ALHONEN, Leena, HALMEKYTÖ, Maria, PORTER, Carl W., JÄNNE, Juhani

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 216 KB

english, 1999

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